This is me one year ago. This is me four months ago. And here I am today. What happened? You know, I used to get a lot of hate, and people were suggesting, you know, I was one step away from death. That caused a lot of reflection, and then I

was like, okay, so how did we get here? If you remember when I started this project, we were trying to evaluate how close we are to being able to stop death. And the way we did that is we looked at all the scientific evidence on what you

could do to slow down and reverse aging damage. And one of these therapies is known as caloric restriction, which means if a person like me consumes 2,500 calories a day to maintain the same weight, you'd reduce that. And so my caloric intake was

1,950 calories, substantially less. This caused me to lose a lot of fat, including in my face, so people started comparing me to Tilda Swinton. Now, this was about two years into the project, and we were pretty ecstatic. The biomarkers we had achieved in me were pretty stunning.

Remember, I was 43 years old when I started. I had led a life of poor health habits as a kid, uh, 20 years of running myself into the ground as an entrepreneur, 10 years of chronic depression. I was in a really bad state

of health. And in just two years' time, we turned it all around. My biomarkers were fantastic. We were excited. But when I went out in public, people were like, like, wait, is this guy going to die? So there was a big disconnect between the success

we were feeling as a team and the perception is that facial fat is really important to how someone gauges someone else's youthfulness. The problem was no matter how good my biomarkers were, they would look at my face and say that guy's old. So in

response we said we're going to do Project Baby Face. We know that in our youth we have a lot of facial fat that over time it lessens. In fact, in your 20s you start losing 1% of your collagen every year. So by the time you're 80

years old you've lost 75% of what you had in your early 20s. We wondered could I rejuvenate my face so I had much more volume? It's endless fun. I love every second of it. Now that is a hard problem. You probably

are aware that people use things like fillers to compensate for the loss of volume. It's why a face can look plump and round, but it's just filler. It's just masking the problem. We wanted to figure out if we could use legitimate rejuvenation technologies to restore

volume in my face. There are five things I did to restore volume in my face. The first thing I did is Sculptra, which is a biostimulator. It's injected into certain regions of the face, for example the temples, right around the mouth, through here. It's designed to allow your

body to naturally produce collagen. So instead of putting filler in the face which just expands in volume, you're getting actual collagen production. My protocol has been doing two vials every 6 months. I think the company recommends one per year, so I've exceeded what they're recommending. Also, I was

compensating from a place of pretty serious deficit, not starting as a maintenance mode of one vial per year at say age 28 and going through time. I didn't do any until I was age 46 and I lost a lot of weight, so I've been trying

to play a little catch-up, but sculpture is first. Next is I tried RUA, which is fat transfer. Now ideally, you want to use your own fat. The problem was I didn't have enough fat on my body to do a transfer, and the doctor was concerned

that if we tried to extract any fat I had, I would leave an indentation on my body. And so I used a donor's fat. When I did this, I had an extreme allergic reaction. In fact, the first day I did it, I met up with a reporter to do a story for

Bloomberg, and on my way home I blew up. I couldn't even see out of my eyes. I called him. I said, 'Just a heads up, I'm going to show up. It's me, you may not recognize it, but don't be scared because of the allergic reaction.' We discontinued

it. Now, sadly it was a promising technology. Uh, we were excited about it and we thought it might be a really good path to revolumize, but because I reacted so profoundly, we just couldn't continue it. So that stopped after one therapy. Next is we decided to increase my daily

caloric intake, going from 1,950 to 2,250. And we were probing, 'Can we increase my calories while also maintaining the same biomarkers and also putting on more fat?' And it worked. I gained 15 lb, just under 7 kg, and that

helped revolutionize my face I'll also note that uh my life substantially improved with a few more calories at 1950 you're in a pretty serious deficit you're hungry all the time it's kind of painful but I signed up for this and I was

willing to do anything in order to achieve the objective uh 1950 it turns out it was not necessary as far as we can tell to achieve the same level of biomarkers so this is a good example of the experiment we're doing where if

caloric restriction is a promising idea and it's still emergent then we're trying this out and we're measuring a bunch of biomarkers if it doesn't need to be 20% then we can move to 10 if it doesn't need to be 10 we can move

to zero it's still very early in the days of anti-aging and so these kinds of experiments I think are at least interesting as a data point on how we think about the therapies and what impact they can have on our lifespans and health spans next is I lessened my

intake of lutein which is a carotenoid from 20 milligrams to 15 and so I did that because it was making my skin yellow and I think this is why so many people were confused they saw me I looked gaunt I was yellow and they're

trying to make sense is this really what a healthy person looks like and so a lot of people were thinking I had liver failure that I didn't know about but it was simply because I had too much carotenoids in my diet and of course that I was on too much calorie restriction

finally I did under eye PRF and that is when you do a blood draw and you separate the red blood cells from the plasma and then you put the plasma back in the body and this is what I did for my sprained ankle it's what you can do

for hair growth which I don't do anymore you can also do for under eye and so over time you lose volume under your eye and there's only really two ways to revolumize one is with filler the other is it's under eye PRF the problem with

filler is it can migrate and become a nightmare so I would strongly recommend you do not do filler under eye it can be very complicated under eye PRF is helpful because it helps revolumize the loss volume also it only lasts for like 3 to

6 months so it needs to be something you repeat on a continued basis but it does in fact work and revolumize what you see disappear over time with age and I do under eye PRF three times per year right now the past few years has been wild

when I started Blueprint I did not expect it to be a global phenomena I did not expect to be scrutinized by everyone in the world I did not expect to be compared to the most aesthetically pleasing beautiful people in the world people who have been on top of their

aesthetic game their entire life growing up in a small community no one really cared about aesthetics you're just expected as you age to get fat go bald so I didn't apply face cream for example ever in my entire life until I was in my

early 40s I never played the aesthetics game and it only of course became relevant when I started this endeavor and aesthetics became a meaningful part, it's been a complicated one because I've been trying to of course demonstrate something that's never been done before

and so it's hard of course for people to understand context, I do think we are at this meaningful moment in time where we are evolving as a species into something else and I'm trying to indicate that this is a promising path for us to pursue, and so sometimes I do feel uh

saddened that the project is by itself evaluated solely on face fat or some other aesthetic component and not upon these you know comprehensive biomarkers we have, but you know what this movement needs to succeed and to do that there are some criteria including volume and a

face that need to be met, I understand I mean the objective was can I be biologically similar to my 18-year-old in every way shape or form, now that sounds inconceivable today but with enough time is it that is a question I

think worth asking as we head into into the future, many of our preconceived notions may be challenged by things that come to pass and when they do I think it's going to be best for all of us to say you know what I have an idea about

reality, but I'm wide open to thinking differently and I think aging and health and wellness is going to be one of those things, so it's a reminder to me to always check assumptions check my beliefs because something may be hiding that may really be in my best interest

if I could just see it be well if you want to see how my body has changed throughout my life check out this video here

I Tried To Make My Face Younger

Bryan Johnson is the world's most measured human. Johnson sold his company, Braintree Venmo, to PayPal for $800m in 2013. Through his Project Blueprint, Johnson has achieved metabolic health equal to the top 1.5% of 18 year olds, inflammation 66% lower than the average 10 year old, and reduced his speed of aging by the equivalent of 31 years. 

Johnson freely shares his protocols and data publicly for everyone to use. Project Blueprint, is an endeavor to achieve humanity and earth scale cooperation starting within Self. 

Johnson is also the founder of Kernel, creator of the world’s first mainstream non-invasive neuroimaging system; and OS Fund, where he invested $100M in the predictable engineering of atoms, molecules, and organisms. He is an outdoor adventure enthusiast, pilot, and author of children’s books, Code 7 and The Proto Project.



Bryan Johnson

초기 프로젝트 목표와 예상치 못한 대중의 반응

처음에는 건강에 대한 비판과 우려에 직면했던 연사가 1년에 걸친 자신의 신체적 변화에 대해 이야기합니다.

이 프로젝트는 노화 손상을 늦추고 되돌림으로써 사망을 막을 수 있는 가능성을 평가하는 것을 목표로 했습니다.

칼로리 제한이 시행되어 체중이 크게 줄고 외모가 변했습니다.

2년 후 놀라운 바이오마커 개선을 달성했음에도 불구하고 대중은 그의 외모 때문에 건강하지 않다고 인식했습니다.

발표자는 프로젝트 전 자신의 좋지 않은 건강 습관에 대해 자세히 설명합니다.

프로젝트 베이비 페이스: 얼굴 볼륨 복원

이 프로젝트는 생체 지표와 인지된 나이 사이의 불일치로 인해 화자의 얼굴을 젊어 보이게 하는 데 초점을 맞췄습니다.

이 프로젝트는 나이가 들면서 잃어버린 얼굴 볼륨을 회복하는 방법을 탐구했습니다.

얼굴 볼륨을 회복하기 위해 다섯 가지 방법을 사용하여 문제를 가리는 것이 아니라 진정한 회춘을 목표로 했습니다.

콜라겐 생성을 촉진하기 위해 생체 자극제인 스컬프트라를 사용했습니다.

RUA(지방 이식)를 시도했지만 심각한 알레르기 반응이 발생하여 사용을 중단했습니다.

칼로리 섭취량이 2,250 칼로리로 증가하여 체중이 증가하고 얼굴 모양이 개선되었습니다.

연사는 이 과정의 실험적 특성과 바이오마커 결과를 바탕으로 칼로리 제한을 조정하는 방법에 대해 설명합니다.

피부 황변을 해결하기 위해 루테인 섭취량을 줄였습니다.

눈 밑 볼륨을 회복하기 위해 눈 밑 PRF를 사용했습니다.

프로젝트와 대중의 인식에 대한 성찰

연사는 이 프로젝트가 예상치 못한 세계적인 관심과 조사를 받았다고 회고합니다.

연사는 새로운 개념을 입증하는 데 따르는 어려움과 광범위한 과학적 맥락을 전달하는 데 따르는 어려움에 대해 설명합니다.

연사는 운동의 성공에 있어 미학의 중요성과 특정 기준을 충족해야 할 필요성을 인정합니다.

화자는 18살의 자신과 생물학적 유사성을 달성할 수 있는 가능성에 의문을 제기합니다.

연사는 노화와 건강에 대한 선입견에 도전하고 새로운 가능성에 열린 자세를 유지하는 것이 중요하다고 강조합니다.

발표자는 시청자가 자신의 가정과 신념을 점검해 보도록 권장합니다.