개 심장사상충 약물의 위험성

심장사상충 치료제는 잠재적인 위험성이 있으므로 반려동물의 안전과 건강을 위해 신중하고 최소한의 사용만 권장합니다.

### 심장사상충 치료: 심장사상충 치료제의 중요성, 부작용 및 안전한 예방법
* 💊 약물 치료는 교통사고와 같은 응급 상황이나 뇌 손상을 예방하기 위해 **고열을 낮출 때와 같이 이점이 해로움보다 클 때** 필요합니다.
* 💊 그러나 약물을 너무 쉽게 처방하고 사용하다 보면 **내성이 생기고 더 강한 약물에 의존**하게 되는 경우가 많습니다.
* 💊 하트가드, 어드보케이트, 프로하트 12와 같은 심장사상충 치료제는 **진정한 예방약이 아니라 심장사상충 유충을 죽이는 치료약**입니다.
* 💊 제약 회사는 심장사상충 치료제의 **단기적인 부작용**을 나열하고 있지만 **장기적인 효과**는 거의 알려지지 않았습니다.
* 💊 FDA에 보고된 모든 약물 부작용의 **약 48%가 심장사상충 치료제로 인해 발생**하며, 이는 해당 약물의 독성을 나타냅니다.
* 💊 프로하트 12(구 프로하트 6)와 같은 주사형 심장사상충 치료제는 **2000년대 초반에 사망을 포함한 심각한 부작용**이 보고된 바 있습니다.
* 💊 가능한 한 **심장사상충 약의 사용을 최소화**하고 더 안전한 예방법에 대해 알아두는 것이 좋습니다.
* 🌡 심장사상충은 성장과 번식을 위해 특정 온도 조건이 필요하므로 **반려견이 자라는 지역의 환경 조건**을 확인하는 것이 중요합니다.

Hello, I'm a veterinarian dad. Today is the fourth session of the heartworm video series. I will inform you about the importance and side effects of the heartworm prevention. All drugs are poisons. All drugs have side effects. Then why do we use these drugs? Why do hospitals prescribe drugs? It is true that there are cases where drugs are absolutely necessary. When we use medication, there are side effects, but the benefits we gain from them are greater than the harm. In such cases, we should use medication. For example, in emergencies like traffic accidents, we need emergency surgery, so we take anesthesia, and we also use anti-inflammatory and painkillers or antibiotics. In these cases, we must use medication. Moreover, if the fever rises and reaches over 40 degrees, but the fever doesn't go down, it can cause damage to the brain. Therefore, we need to temporarily lower the fever with antipyretics.

Medication is necessary, but the problem is that it is prescribed and used too easily, even when it may not be absolutely necessary, and there are other ways to treat it sufficiently. When we catch a cold, have diarrhea, vomit, or get a skin disease, not only humans but also animals are prescribed medication too easily. However, the problem is that if this medication is repeatedly administered, resistance to the medication develops, and the body no longer responds to it. Then, stronger and more potent medication needs to be used. As a result, the body's natural healing power, which can heal itself, gradually weakens, and the body becomes dependent on the medication. Therefore, those who continue to use this medication will gradually weaken and become more vulnerable to diseases. What about kidney disease?

Yes, that's right. When it comes to heartworm medication, there are three important types. First, there is a form that we easily give to dogs orally, in a tablet form. Its main ingredient is Ivermectin. Then, there is another type called Advokate, a product from the past. Its main ingredients are Imidacloprid and Moxidectin. Lastly, there is a product called ProHeart 12, which comes in an injectable form. The main ingredient of this is Moxidectin. So, what is the role of these medications? These are considered heartworm preventive medications, but strictly speaking, they are not preventives but rather treatments that kill heartworms. They are medications that kill the larvae in the heart, so the components of these medications paralyze the heartworms and kill them. If the worm itself is toxic, naturally, the medication to eliminate them would also have toxicity.

The pharmaceutical company mentions the side effects of heartworm medication as follows: for Heartguard, the side effects include depression, lethargy, vomiting, loss of appetite, diarrhea, dilated pupils, muscle weakness, staggering, seizures, excessive salivation, and so on. However, these side effects belong to short-term adverse reactions. In other words, the company only conducts research on side effects that occur within a few weeks to several months in terms of the drug's safety. Long-term side effects, such as those that may occur years later, are practically impossible to study. Therefore, we truly have very little knowledge about the long-term side effects. Hence, we do not know if this heartworm medication may have any harmful effects on animals in the long run.

Repeated administration can weaken the dog's immune system, making it vulnerable to other diseases. According to a report from the FDA, about 48% of all drug side effects are caused by heartworm medications, indicating that these drugs are more toxic compared to others. Therefore, we need to be very careful and thoughtful when using these medications. Feeding heartworm medication does not guarantee that the dog will not get heartworm disease. In some parts of the United States, an experiment was conducted over ten years. They compared the incidence of heartworm disease in dogs that were given heartworm medication and those that were not. They found that there was little difference in the incidence rate. Why is that? It is because repeated exposure led to the development of resistance to the medication due to continuous bleeding.

And due to these changes in the environment, mosquitoes continue to increase exponentially, and with the repetitive administration of drugs, and then involvement in preventive measures, are there preventive measures such as vaccines for dogs? As the immunity of dogs decreases, their resistance does not decrease, and it continues to increase. And we specifically mentioned earlier that there are three types of heartworm medications: oral, topical, and injectable. We need to be particularly cautious about injectables. The injectable medication called f is currently on the market under the name Art 12. Once this injection is administered, its effects last for about a year. Therefore, from the perspective of guardians, due to the inconvenience of having to take medication every month, many opt for this injection. When using this, serious consideration is required.

Because in the early 2000s, it was not released as 2% art 12, but under the name Pro Art Six. After that, for about 3 to 4 years, serious side effects of this drug were reported. These side effects include anaphylactic shock, rapid increase in liver enzymes, various immune-related autoimmune diseases, heart valve damage, adipocyte tumors, lymphoid tumors, tissue structure abnormalities, and even death. About 5500 cases, including about 600 deaths, were reported only in the United States. Therefore, the FDA decided to discontinue the sale of this drug. However, in 2008, the FDA allowed the sale of this drug again. Initially, this drug, which can be taken for six months, was called Pro Art Six.

Art 12 has changed to a baseball that can last about a year, and this has been approved. Even if you think about it sensibly, it's really hard to understand. The main ingredient, Moxi, is said to contain about three times more than Exis. However, the problem is that once you take this medicine, you can never remove the drug from your body. Unintentionally, the effects of this medicine last for about a year. Therefore, I personally do not sell or use this medicine. Among the forecasters, there are some who ask for this medicine a little, but due to its significant side effects, I do not use it. So, for more details, please refer to the translated texts in that block. Therefore, I will inform you about the side effects and dangers of this heartworm medicine.

Despite the information I provided, I still think it would be better to give medicine until the end. It's good to hear people asking for medicine. However, if someone chooses not to take it, I cannot force or stop them. But it is best not to use medicine. However, if you must use it, you should try to reduce the frequency of taking the medicine as much as possible. This applies to those who give heartworm medicine. Before giving this medicine, there are two facts we need to know. We need to know how heartworms reproduce. For heartworms to reproduce, three conditions must be met. Firstly, the average temperature must be above 14 degrees Celsius. Secondly, the temperature must be above 24 degrees Celsius continuously for more than 45 days, and the temperature must be above 26 degrees Celsius for at least two weeks. Only when these three conditions are met can heartworms grow and reproduce. However, if any one of these three conditions is not met, it will not be possible.

If it does not meet the requirements, the heartworm cannot grow. So, please check the temperature and environment of the area where you are raising your dog, and try to minimize the use of this medicine as much as possible. Dr. Park, a representative of the Heartworm Association, says that it is unnecessary for animals in all areas to take heartworm medicine every month. However, except for warm regions in the United States such as Florida and Texas, in other regions, it is necessary to give the medicine every month. If side effects occur due to this heartworm medicine, in most cases, veterinarians will not take responsibility unless it is a serious situation. Ultimately, the guardian must take all responsibility and bear the cost. Therefore, please be careful when administering this medicine or choosing any other medication.

Please consider and conduct research before taking medication. Therefore, please try to minimize the use of this heartworm medication as much as possible and learn about safer preventive methods. We will inform you about safer ways to prevent heartworm disease next time. Please prevent heartworms in a safer way and regularly check to prevent this disease. In the next session, we will explain how to test and diagnose kidney disease. Thank you.

심장사상충영상 시리즈 4. 심장사상충약의 부작용과 위험성

시골에서 작은 동물 병원을 운영하고 있는 수의사입니다. 질병의 근본적인 원인을 이해하고 부작용이 적은 천연 치료법을 통해 동물의 건강을 지키려고 노력하고 있습니다. 그리고 크리스천으로서 살아가는 이야기, 결혼과 자녀 교육에 대한 경험과 생각들을 나누고 싶습니다^^

수의사아빠

수의학 치료에서 약물의 중요성과 오남용

동물 치료에서 약물은 중요하지만 남용하면 내성과 의존성을 유발할 수 있습니다.

쉽게 처방되는 약물은 신체의 자연 치유력을 약화시켜 질병에 더 취약하게 만들 수 있습니다.

개를 위한 심장사상충 치료제는 이버멕틴이 함유된 경구용 정제, 이미다클로프리드와 목시덱틴이 함유된 어드보케이트, 목시덱틴이 함유된 주사제 프로하트 12 등 세 가지 중요한 유형이 있으며, 모두 심장사상충을 마비시켜 죽이는 작용을 합니다.

심장사상충 치료제의 장기적인 부작용에 대한 제한된 이해

제약 회사는 심장사상충 치료제의 단기적인 부작용만 연구하기 때문에 장기적인 효과에 대한 지식이 거의 없습니다.

약물을 장기간 사용하면 개의 면역 체계가 약화되고 내성이 생길 수 있으며, 약을 먹은 개와 먹지 않은 개에서 심장사상충 발병률에 거의 차이가 없다는 연구 결과도 있습니다.

또한 이 약은 상당한 비율의 약물 부작용을 유발하는 것으로 보고되어 잠재적인 독성을 나타냅니다.

반려견 심장사상충 치료제에 대한 논란

모기 개체 수가 증가함에 따라 반려견을 위한 예방 조치와 약물의 중요성이 커지고 있습니다.

사용 가능한 약물 중 하나인 Art 12라는 주사제는 심각한 부작용으로 인해 FDA에서 판매 중단을 결정했지만 나중에 다시 시판이 허용되었습니다.

약 1년 동안 효과가 지속되는 이 주사는 편리하다는 이유로 많은 반려견 주인이 선택하지만, 과거 문제가 있었기 때문에 신중하게 고려하는 것이 좋습니다.

오래 지속되는 심장사상충 치료제의 승인과 위험성

쑥을 주성분으로 하는 Art 12라는 새로운 심장사상충 치료제가 승인되었으며, 체내에서 약 1년간 약효가 지속됩니다.

이 약은 심각한 부작용이 있어 효과가 오래 지속되기 때문에 최소한의 사용을 권장하고 있습니다.

심장사상충 번식은 특정 온도 조건에 따라 달라지며, 이는 약의 필요성에 영향을 미칠 수 있습니다.

심장사상충 치료제의 책임감 있는 사용

심장사상충 협회 대표인 박 박사에 따르면 모든 지역에서 심장사상충 치료제가 필요한 것은 아니라고 합니다.

미국에서는 일반적으로 플로리다와 텍사스와 같은 따뜻한 지역에서는 필요하지만 다른 지역에서는 필요하지 않습니다.

부작용과 비용에 대한 책임은 전적으로 보호자에게 있으므로 약 사용을 최소화하고 더 안전한 예방 방법을 연구하는 것이 중요합니다.