According to several studies to date, phosphatidylserine is helping to improve cognitive function. Hi everyone, I am Son Je-yong, a neurology specialist, and this is [Dr. Son’s Neurology Playlist]. With the rapid aging of the world's population, including our country, cognitive decline is becoming a serious problem. Every year, 10 million patients around the world are diagnosed with dementia. The general public, not medical personnel, is also interested in this cognitive decline. In particular, recently, there have been a lot of advertisements and TV shows about phosphatidylserine, a nutritional supplement for brain health. Perhaps because of that, several patients have often asked about phosphatidylserine recently.

Several patients have often asked about phosphatidylserine recently. Phosphatidylserine is one of the amino phospholipid molecules. This component is an important part of the cell membrane surrounding the cells in our body and affects cell death and cell signaling. Phosphatidylserine is particularly abundant in the brain, and about 15% of the brain's total phospholipids are present. About 30 grams are present in the human body, of which about 13 grams are present in brain tissue. It has several functions in the brain. It regulates various substances that stimulate the survival and growth of cranial nerve cells and the connection of cranial nerve cells. And sending several neurotransmitters inside brain cells out of the cell is called exocytosis.

which regulates exocytosis and also regulates receptors for a substance called glutamate that affects the excitation activity of the brain. That affects the excitation activity of the brain. I think it'll sound too difficult to say this. I think it'll sound too difficult to say this. In conclusion, phosphatidylserine is abundant in the brain and is a component that makes up the cell membrane outside nerve cells. It is in the cell membrane and regulates various neurotransmitters from the brain and accepts them. There are many kinds of neurotransmitters. Some of them are related to cognitive function and memory. Some of them are related to cognitive function and memory. Phosphatidylserine exists in animals and plants. Phosphatidylserine exists in animals and plants. Other than nutritional supplements, foods commonly consumed are high in soy and milk. Foods commonly consumed are high in soy and milk. Corn, almonds, and sunflower oil have a little phosphatidylserine.

and sunflower oil have a little phosphatidylserine. Phosphatidylserine is high in cow endothelium, beans, and eggs. Currently, phosphatidylserine from soybeans is used in nutritional supplements. According to several studies to date, phosphatidylserine has helped improve cognitive function. Phosphatidylserine has been widely used as a nutritional supplement for brain health these days, and studies related to it have been conducted since the late 1980s.

In a 1986 study on the effects of phosphatidylserine on dementia patients, there were quite a few improvements in behavior in the group that took phosphatidylserine. There have been several such studies since then, most of which had a dose of phosphatidylserine of 300 mg per day. There was also a study in which 300 mg of phosphatidylserine per day was administered to elderly patients with cognitive decline for 6 months, and significant symptom improvement was observed in behavior and cognitive function. Some studies have shown that it works like this,

but some studies have shown that it has not been very effective on the dementia scale. Perhaps these results differ according to the severity. Perhaps these results differ according to the severity and progression of dementia in patients given phosphatidylserine. and progression of dementia in patients given phosphatidylserine. Re-analyzing the results of studies related to phosphatidylserine as a whole, Re-analyzing the results of studies related to phosphatidylserine as a whole, it seems to have some effect, especially on memory. However, the impact on the ability to carry out daily life was not clear. However, the impact on the ability to carry out daily life was not clear. In conclusion, phosphatidylserine appears to be of some help in improving cognitive function, phosphatidylserine appears to be of some help in improving cognitive function, especially related to memory, when taking 300 mg per day and without any specific side effects.

especially related to memory, when taking 300 mg per day and without any specific side effects. However, it is still unknown how effective it is for the ability to carry out real daily life. It is still unknown how effective it is for the ability to carry out real daily life. So far, there are no exact clinical studies related to these nutritional supplements in practice. So far, there are no exact clinical studies related to these nutritional supplements in practice. It targets each patient with cognitive decline, but it may be due to the difference in the degree of cognitive decline, or it may be due to the lack of a significant effect. This leads to an ambiguous conclusion as to whether This leads to an ambiguous conclusion as to whether or not to take this nutritional supplement. In fact, nutritional supplements, in my opinion, are not completely ineffective if you look at them for each efficacy. are not completely ineffective if you look at them for each efficacy. However, in most cases, they are not as effective as drugs prescribed

In most cases, they are not as effective as drugs prescribed and taken at the hospital. Phosphatidylserine is the same as other nutritional supplements. The mechanisms of drugs and clinical studies show that phosphatidylserine is helpful for memory-related parts of brain function. Phosphatidylserine is helpful for memory-related parts of brain function. However, for clinical use in patients with dementia or cognitive decline, more studies are needed. For clinical use in patients with dementia or cognitive decline, more studies are needed. For clinical use in patients with dementia or cognitive decline, more studies are needed. For clinical use in patients with dementia or cognitive decline, more studies are needed. And there is no significant improvement in actual daily performance. And there is no significant improvement in actual daily performance given the results of studies to date. I think nutritional supplements and supplements can be taken with related therapeutic drugs. I think nutritional supplements and supplements can be taken with related therapeutic drugs. But I think it's better not to expect too much.

But I think it's better not to expect too much. Phosphatidylserine may be equally helpful for memory, but more important than this is an accurate diagnosis of current cognitive decline and the subsequent use of related medications. That's all for today, and I'll wrap up here. If today's content was helpful, please subscribe, like, and turn on notifications for Dr. Son’s Neurology Playlist. Thank you.

[포스파티딜세린] 뇌영양제? 먹어야 할까? 말아야 할까? ([Phosphatidylserine] Brain supplements? Should I take them or not?)

신경과 전문의 손제용의 [손제용의사생활]