Monitoring Gastric Cancer Recovery: Challenges and Guidelines

Monitoring Stage II and III gastric cancer patients is essential for effective care and improving survival rates.

### Tracking Recovery After Subtotal Gastrectomy for Gastric Cancer
The Buddha announced an exemption for the four-year requirement, and the National Cancer Center is responsible for this. A male patient with **D3 stage gastric cancer** underwent surgery and showed a **slight increase in tumor markers**, leading to **palliative care** after peritoneal metastasis was detected. Follow-up approaches for patients vary widely, with no standardized method, raising concerns about the **effectiveness of early detection and treatment in improving survival rates**.

### Evaluating Gastric Cancer Treatment and Follow-Up
Gastric cancer treatment involves around **23,000 patients annually** needing regular procedures, with a significant cost of approximately **370 billion** for follow-up examinations. The research team struggled to establish guidelines for follow-up due to a **lack of evidence**, leading to their exclusion from recommendations. Different countries have varying approaches to treatment and follow-up, with no definitive answer on how to address stomach cancer, highlighting the need for a **more effective utilization of resources and strategies**.

### Stove Colorectal: A Nationwide Study on Stage II and III Cancer Patients
The Stove Colorectal project is a large-scale study involving **16 institutions across the country**, focusing on Stage II and III cancer patients who have undergone surgery. The study aims to **increase the frequency of patient visits** and is conducting follow-ups at **3 and 6-month intervals**, with an estimated **6% difference in outcomes**. Researchers are analyzing **survival rates and quality of life** separately, while facing challenges in **obtaining patient consent** for the study.

### Compliance and Study Design for Cancer Research
The study aims to **maintain patient compliance** through a three to six-month period, with a primary endpoint of a **three-year overall survival rate**. Tests will be conducted in Korea, focusing on **recurrence survival analysis** and **nutrition assessments**, while major hospitals collaborate to register **stage two patients**. Monitoring patients at stages two and three is emphasized as **crucial for effective care** and establishing **evidence-based guidelines globally**.

### Challenges and Strategies in Research Funding
The speaker highlights the **significant differences** in the current generation's approach to research and the **importance of incentives**, which are tied to national research funding. They discuss the **tight timeline** of a five-year project, emphasizing the **challenges of aligning research** with this timeframe. The speaker expresses hope for **improved support and meaningful outcomes**, while planning to provide research support based on a **well-managed database**.

### Tracking Recovery in Advanced Gastric Cancer Patients Post-Surgery
* 🏥 The discussion begins with the announcement of an **exemption regarding the four-year requirement** by the Buddha, leading to a focus on **patient recovery tracking** at the National Cancer Center.
* 👨 A personal case study of a male patient who underwent subtotal gastrectomy for advanced gastric cancer (stage D3) illustrates the **challenges in monitoring tumor markers** and the subsequent decision to provide **palliative care after detecting peritoneal metastasis**.
* The importance of early detection of recurrence through follow-up observations is emphasized, as this can lead to **aggressive treatment** and potentially **improve survival rates**.
* 📊 A survey conducted at Inje University revealed varied follow-up practices among doctors, with recommendations ranging from **every three months to once a year**, highlighting the **lack of standardized approaches**.
* 💰 The financial implications of follow-up procedures are significant, with estimates suggesting that **regular examinations for approximately 23,000 patients annually** could cost around **370 billion won**.
* 🌍 Comparisons with international guidelines reveal that while Japan and other countries have established recommendations, Korea lacks a definitive standard, leading to **inconsistencies in patient management**.
* 🔬 A multi-center study involving 16 institutions aims to analyze the survival rates and quality of life of Stage II and III cancer patients, with a primary endpoint of the **three-year overall survival rate**.
* 📅 The study design includes rigorous follow-ups every three to six months, with a focus on **establishing evidence-based guidelines and improving patient care** while **managing societal costs efficiently**.

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[대한소화기학회-PACEN 공동 심포지엄] ③ PACEN 지원 소화기질환 분야 연구 및 예상성과 소개(2) (류근원 국립암센터)

[대한소화기학회-PACEN 공동 심포지엄] ③ PACEN 지원 소화기질환 분야 연구 및 예상성과 소개(2) (류근원 국립암센터)